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(Blood disease modeling unraveling the pathogenic mechanism and drug development)
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(Generation and applications of human pluripotent stem cell-derived bone marrow organoids)
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(Identification of development and heterogeneity of hematopoietic stem progenitor cells)
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Jeong HC*, Shukla S*, Fok WC, Huynh TN, Batista LFZ, Parker R ¡°USB1 is a miRNA deadenylase that regulates hematopoietic development¡± Science. 2023 379(6635): 901-7.
(Research Highlighted by Nature Review Genetics: https://www.nature.com/articles/s41576-023-00595-9)
Jeong HC*, Go YH*, Shin JG, Kim YJ, Cho MG, Gwon D, Cheong HS, Lee H, Lee JH, Jang CY, Shin HD, Cha HJ ¡°TPX2 amplification-driven aberrant mitosis in culture adapted human embryonic stem cells with gain of 20q11.21¡± Stem Cell Rev Rep. 2023 doi: 10.1007/s12015-023-10514-4.
Shukla S*, Jeong HC*, Sturgeon CM, Parker R, Batista LFZ ¡°Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita¡± Blood Adv. 2020 4(12): 2712-22.
Jeong HC, Park SJ, Choi JJ, Go YH, Hong SK, Kwon OS, Shin JG, Kim RK, Lee MO, Lee SJ, Shin HD, Moon SH, Cha HJ ¡°PRMT8 controls the pluripotency and mesodermal fate of human embryonic stem cells by enhancing the PI3K/AKT/SOX2 axis¡± Stem Cells. 2017 35(9): 2037-49.
Jeong HC, Cho SJ, Lee MO, Cha HJ ¡°Technical approaches to induce selective cell death of pluripotent stem cells¡± Cell Mol Life Sci. 2017 74(14): 2601-11. (Invited Review)
Yea CH*, Jeong HC*, Moon SH, Lee MO, Kim KJ, Choi JW, Cha HJ ¡°In situ label-free quantification of human pluripotent stem cells with electrochemical potential¡± Biomaterials. 2016 75: 250-9.
Jeong HC, Gil NY, Lee HS, Cho SJ, Kim K, Chun KH, Cho H, Cha HJ ¡°Timely degradation of Wip1 phosphatase by APC/C activator protein Cdh1 is necessary for normal mitotic progression¡± J Cell Biochem. 2015 116(8): 1602-12.