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  • ȨÆäÀÌÁö ¹Ù·Î°¡±â http://biomed.skku.edu/jeeahn
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  • ¿¬¶ôó     £ü (ÀüÈ­) 031-299-6134 / (fax) 031-299-6139
  • À̸ÞÀÏ     £ü jeeahn@skku.edu

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  • 1991-2000 ÇѸ²´ëÇб³ ÀÚ¿¬°úÇдëÇÐ À¯Àü°øÇаú Çлç/¼®»ç/¹Ú»ç
    2002-2004 Emory University School of Medicine, USA. Post Doctoral Fellow
    2011-2012 University of California San Francisco (UCSF) School of Medicine ¹æ¹®±³¼ö
    2005-ÇöÀç ¼º±Õ°ü´ëÇб³ ÀÇ°ú´ëÇÐ Á¶±³¼ö/ºÎ±³¼ö/±³¼ö

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  • º» ¿¬±¸½ÇÀº ³ú¹ß´Þ°ú Áúȯ¿¡¼­ Áß¿äÇÑ ½Å°æ¼¼Æ÷ÀÇ ¹ß»ý, »ç¸ê, ¹× ½Ã³À½º Çü¼º Á¶ÀýÀÇ ±Ùº»Àû ±âÀÛ°ú ¿ø¸® ±Ô¸íÀ» ¸ñÇ¥·Î ÇÏ°í ÀÖÀ½.
    Áö³­ ¼ö ³â°£ ¿ì¸® ¿¬±¸½Ç¿¡¼­´Â ½Å°æ¼¼Æ÷ÀÇ ¹ß´Þ°ú »ç¸êÀ» Á¶ÀýÇÏ´Â ÁÖ¿ä ÀÎÀÚµéÀ» ¹ß±¼ÇÏ¿´°í À̵éÀÇ Á¶Àý±âÀü¿¡ °üÇÑ ¿¬±¸¸¦ ¼öÇàÇØ ¿ÔÀ½. À̸¦ ±â¹ÝÀ¸·Î ÇöÀç´Â ³ú¹ß´Þ°ú ³úÁúȯ (ÅðÇ༺Áúȯ/¹ß´ÞÀå¾Ö/ÇãÇ÷¼º ³úÁúȯ/³ú¾Ï)¿¡¼­ ½Å°æ°è ¹ß´Þ Á¶Àý°ú ÁßÃ߽Űæ Àç»ýÁ¶Àý¿¡ ´ëÇÑ ½Éµµ ÀÖ´Â ¿¬±¸¸¦ ÁøÇàÇÏ°í ÀÖÀ½. ´Ù¾çÇÑ in vitro ½ÇÇè/organotypic slice culture/knock-out mice ÀÌ¿ëÇÑ ex vivo/in vivoÀÇ mix-match ¿¬±¸¸¦ ¼öÇàÇÏ°í ÀÖÀ½. ¿¬±¸ ÁÖÁ¦´Â Å©°Ô 1) ³ú¹ß´Þ/ÁúȯÀÇ ÈļºÀ¯Àü Á¶Àý¿¬±¸, 2) ³ú¹ß´ÞÀå¾Ö ¹× Áúȯ ¸ðµ¨¿¡¼­ ´º·± ¹ß»ý°ú »ç¸ê Á¶Àý¿¬±¸ 3) CNS ¼Õ»ó ½Ã axon Àç»ý Á¶Àý¿¬±¸ µîÀ¸·Î ³ª´­ ¼ö ÀÖÀ½.

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  • 1.Ko et al.,(2019) Roles of ErbB3 binding protein 1 (EBP1) in embryonic development and gene-silencing control Proc Natl Acad Sci. 116 (49) 24852-24860

    2.Ko et al.,(2019) SIAH1 ubiquitin ligase mediates ubiquitination and degradation of Akt3 in neural development. J. Biol. Chem. 294(42):15435-15445

    3.Ahn et al.,(2018) Vascular endothelial growth factor in mediating therapeutic efficacy of mesenchymal stem cell derived exosomes against neonatal hyperoxic lung injury Experiments and Molecular Medicine 1350(4):26

    4.Ko et al, (2018) Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling Stem cell research and Therapy 219(1):326

    5.Ko et al., (2016) Akt1/Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration eLife 5:e20799

    6.Hwang et al., , (2016) C-terminal domain of p42 Ebp1 is essential for down regulation of p85 subunit of PI3K, inhibiting tumor growth Scientific Reports, 6:30626

    7.Ko et al., 2014, P42 Ebp1 regulates the proteasomal degradation of the p85 regulatory subunit of PI3K by recruiting a chaperone-E3 ligase complex HSP70/CHIP Cell Death and Disease 5, e1131 doi:10.1038/cddis.2014.79

    8.Lee et al., (2012) S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1/GAPDH death cascade J Cell Biol. 199(1) 65-76

    9.Kim et al., (2010) Negative regulation of p53 by the long isoform of ErbB3 binding protein Ebp1 in brain tumors. Cancer Res 70(23):9730-9741

    10.Lee et al., (2008), Nuclear Akt interacts with B23/NPM and protects it from proteolytic cleavage, enhancing cell survival Proc Natl Acad Sci. 105(43) 16584-16589